5 Treatment, Prevention and Summary
Transcript
Dear friends
Greetings to all!
Today we are going to discuss lesson 5, before that up to the last class we have dealt with various Treatments like Manual rupture, Specific treatment for Luteal cyst, Follicular cyst, and general treatment for GnRH and its analogues with PGF2 Alpha and its analogues.
Today we are going to discuss the remaining Treatment available for Luteal cysts and Follicular cysts, Prevention and Control of Luteal cysts and Follicular cysts, and the Summary also.
In the case of Follicular cysts and Luteal cysts, these may be treated with Progesterone based equipment and Prostaglandin based protocols: On Day1, CIDR/PRID/P4, Progesterone sponges may be inserted per vaginally and this CIDR, PRID, and Progesterone contains Synthetic Progesterone, so after insertion, this Progesterone may be observed by the system, which causes suppression of Gonadotropin release; On Day8, administration of PGF2 Alpha should be done, which helps to Lysis of CL or complete formation of luteinized cysts;
On Day9, the sudden withdrawal of these Progesterone P4 devices is to be done, which in turn releases a surge of Gonadotropin release, which helps in the emergence of new follicular waves. Progesterone based treatment protocols Day1 that is Day0, insertion of CIDR + Buserelin Acetate 20 microgram; On Day8 Cloprostenol 500 microgram; On Day9 withdrawal of CIDR to be done; On Day11 Fixed time Artificial Insemination along with Buserelin Acetate 10 microgram, at the time of initiation of treatment you have to give 20 micrograms on Day11 at the time of AI 10 microgram of Buserelin Acetate is sufficient; Day12 again Fixed time Artificial Insemination you can go for pregnancy diagnosis on Day45.
Progesterone alone may be given however administration of Buserelin Acetate along with the insertion of CIDR is having advantages one this Buserelin Acetate involved in the complete luteinization of follicle or ovulation, so it makes such the formation of corpus luteum and that corpus luteum is highly responsive to Prostaglandin injection, so most of the time all the animals coming to estrous, you can achieve more than 60% of conception rate also. Irresponsive Follicular cyst cases: mostly 60% of the cases can respond to the treatment of Hormonal therapy, remaining 20% – 30% that is delayed cases or chronic cases or not having response with the earlier treatment, those cases are treated with ultrasound-guided transvaginal follicular cyst aspiration technique, this is the follicular transvaginal probe(showing picture), that is an ultrasound-guided transvaginal probe with the needle, this should be inserted per vaginally with the help of parental examination, the follicles or the ovaries are guided with your fingers and the needle is inserted and the fluid is aspirated, this is the aspirated fluid(showing picture) it looks like yellow or amber-colored if bleeding occurs it looks pink in color.
This is a technique (showing pictures), it is an intact cystic follicle, so after the insertion of the needle, you can see/visualize the needle present here after respiration is a collapsed follicle is absorbed and then after collapsed follicle within 10 days, 9 to 12 days interval, whatever maybe you can observe the presence of any estrous signs, during that signs you can absorb or visualize the emergence of new follicles present on the ovary, so during this time you can go for Artificial Insemination with Receptal injection 10 micrograms of Receptal is injected and then after 24 hours again repetition of AI should be done and then pregnancy diagnosis made at 45th-day.
Treatment response: here the incidents are concerned, authors have recorded various incidences, so an overall incidence of Follicular cyst and Luteal cyst is about 5-45%, always the Follicular cyst formation is higher than that of Luteal cyst formation and then here 14% of all cows develop a cyst in life, especially during the postpartum condition. In postpartum condition, 20% of the animals after cyst formation can recover spontaneously remaining 40% of the animal go for cyst and delayed ovulation or anovulation or cystic formation. Then postpartum calving to conception interval may be increased, that is recovery changes without treatment is possible in 30-70% of the animals which were recorded by so many researchers.
Treatment response with the Hormonal therapy is possible 60-70% in Follicular cysts, 70-80% in Luteal cysts, and treatment response with Follicular fluid aspiration technique this is only for non-responsive cases that are about 30% in Follicular cyst. So, Prevention and Control: the first one is the culling and selective breeding; this culling and selective breeding are adapted to farm conditions, every year 10% of the culling is highly essential, mostly aged animals and infertile animals, these types of chronically affected cystic ovarian conditions animals, maybe culled, then only the form will be viable. Rational use of Hormones; the hormones should be used rationally because it is like a swad, suppose if you use either a high dose of hormone or a lower dose of hormone, that will affect the reproductive cyclicity of the animal.
Implementation of synchronization technique during the postpartum period may help to improve the conception rate, not only improve the conception rate but also helps to prevent and control cystic ovarian degeneration.
Reducing the length of the postpartum negative energy balance period is highly essential because, in farm conditions, balanced feeding is highly essential. Usually, most of the farms’ scientific feeding schedule is followed, that is up to 5 liter of milk yield they used to give 2 kg or 2.5 kg of concentrate and in addition each 1 liter of milk you have to give half kg of concentrate. Suppose a 10 kg milk production animal is there means, you have to go for 4.5 kg of concentrate then only the negative energy balance will be prevented. and green fodder administration is highly essential, especially during summer 25 kg of Green fodder feeding is highly essential.
Maximizing dry matter intake and reducing protein content in diet especially during postpartum is highly essential to prevent and control the cystic ovarian degeneration condition. Minimizing the occurrence of metabolic diseases is also highly essential.
So far, we have discussed in 5 classes that are: Introduction, Hormonal regulation of ovarian activity, Predisposing factors, Signs and Symptoms, Ultrasonographic images of normal ovarian structures, Classification of cystic ovaries, Mechanism of cyst formation, Signs and Symptoms of cystic ovarian degeneration, Diagnosis and Prognosis, Treatment and Prevention.
Thank you!
